Saúde e pesquisas domiciliares no Brasil e Inglaterra: a Pesquisa Nacional de Saúde e a Health Survey for England / Health and household surveys in Brazil and England: The National Health Survey and the Health Survey for England

Resumo O objetivo do artigo é analisar as características das pesquisas nacionais de saúde realizadas no Brasil e na Inglaterra pelos seus respectivos institutos de Estatística. No Brasil foi considerada a Pesquisa Nacional de Saúde (PNS) e na Inglaterra, a Health Survey for England (HSE). Para tanto, apresenta-se inicialmente um panorama sobre os distintos perfis populacionais dos países. Passa-se, então, a um breve histórico das pesquisas, evidenciando inclusive as temáticas comuns que são abordadas na PNS e na HSE que favorecem análises comparativas. Por fim, apresenta-se uma comparação, a título de exemplo, acerca das desigualdades no acesso e na utilização dos serviços de saúde no Brasil e na Inglaterra. Os resultados evidenciam inúmeras possiblidades de análises comparativas em temáticas como percepção de saúde, tabagismo, consumo de bebidas alcoólicas, diabetes e hipertensão. Entretanto, salienta-se a necessidade de atentar para especificidades do perfil populacional de cada país e às características metodológicas das pesquisas.

Abstract This paper aims to analyze the characteristics of national health surveys conducted in Brazil and England by their respective Statistics institutes. For Brazil, the National Health Survey (PNS) was considered, and the Health Survey for England (HSE) for England. To this end, we show a preliminary overview of the different population profiles of the two countries. Then, a brief historical background is presented, including the common themes that are addressed in the PNS and HSE that favor comparative analyses. Finally, we compared, for example, the inequalities in access to and use of Brazilian and English health services. The results show several possibilities for comparative analysis on topics such as health perception, tobacco use, alcohol consumption, diabetes, and hypertension. However, the need to consider the specificities of the population profile of each country and the methodological characteristics of the surveys is emphasized.

Association of Angiotensin-Converting Enzyme Genotype, Insertion/Deletion Polymorphism and Saphenous Vein Graft Atherosclerosis in Iranian Patients

ABSTRACT OBJECTIVE: The aim of this study was to evaluate possible interactions among Angiotensin-I converting enzyme genotype, insertion/deletion polymorphism and atherosclerosis of vein grafts in Iranian patients, and characterize their clinical and demographic profile. METHODS: In this cross-sectional study, patients who underwent coronary artery bypass graft surgery more than five years ago, were included for angiographic analysis. Atherosclerosis was determined by quantitative angiography and adjusted Gensini score. The gene angiotensin converting enzyme I/D polymorphism was detected by polymerase chain reaction. RESULTS: A total of 102 patients participated in this study. Eighty-four patients were male. The frequency distribution of DD, ID and II polymorphism were 23.6%, 62.7% and 13.7% respectively. There were no differences among genotypic groups in age, sex, number of risk factors, number of vein grafts and months since bypass surgery. According to adjusted Gensini score [0.18±0.12 (II) vs. 0.11±0.09 (ID) and 0.1±0.09 (DD) P=0.021] the II genotype was associated with severity of vein graft atherosclerosis. CONCLUSION: Although there are conflicting results about gene angiotensin converting enzyme I/D polymorphism and the degree of venous bypass graft degeneration, this study suggests an association between ACE genotype II and atherosclerosis of saphenous vein grafts, however, large samples considering clinical, demographic and ethnic profile are necessary to confirm these results.

Disease and weight loss: a prospective study of middle-aged and older adults in Costa Rica and England / Enfermedad y pérdida de peso: un estudio prospectivo de adultos y adultos mayores en Costa Rica e Inglaterra

Objective. To determine whether disease predicts weight loss in population-based studies, as this may confound the relationship between weight and mortality. Materials and methods. We used longitudinal data from the Costa Rican Longevity and Healthy Aging Study (CRELES) and the English Longitudinal Study of Ageing (ELSA). We defined two overlapping outcomes of measured weight loss between waves: >1.0 point of body mass index (BMI) and >2.0 BMI points. Logistic regression models estimated the associations with disease, adjusting for age (range 52-79), sex, smoking, and initial BMI. Results. In ELSA, onset of diabetes, cancer, or lung disease is associated with loss >2.0 points (respectively, OR=2.25 [95%CI: 1.34-3.80]; OR=2.70 [95%CI: 1.49-4.89]; OR=1.82 [95%CI: 1.02-3.26]). In CRELES, disease-onset reports are not associated with weight loss at 5% significance, but statistical power to detect associations is poor. Conclusion. Although it is known that some diseases cause weight loss, at the population level these associations vary considerably across samples.

Objetivo. Determinar si las enfermedades predicen pérdida de peso a partir de encuestas poblacionales, debido a que esto podría confundir la relación entre peso y mortalidad. Material y métodos. Se utilizaron datos longitudinales de Costa Rica: Estudio de Longevidad y Envejecimiento Saludable (CRELES) y Estudio Longitudinal de Envejecimiento en Inglaterra (ELSA, por sus siglas en inglés). Se definieron dos indicadores de resultado no excluyentes de pérdida de peso entre rondas: >1.0 punto de índice de masa corporal (IMC) y >2.0 puntos de IMC. Las asociaciones de interés se estimaron con modelos de regresión logística, con controles para la edad (rango 52-79), sexo, tabaquismo actual e IMC inicial. Resultados. En el ELSA, la incidencia de diabetes, cáncer o enfermedad pulmonar está asociada con pérdida de >2.0 puntos de IMC (respectivamente: OR=2.25 [IC95%: 1.34-3.80]; OR=2.70 [IC95%: 1.49-4.89]; OR=1.82 [IC95%: 1.02-3.26]). En el CRELES, el reporte de diagnóstico de enfermedades no muestra asociación significativa a 5% con pérdida de peso, pero el poder estadístico de la muestra para detectar asociaciones es limitado. Conclusión. Aunque es conocido que ciertas enfermedades causan pérdida de peso, estas asociaciones a nivel poblacional varían considerablemente entre encuestas.

Degeneración quística de la arteria poplítea: Presentación de caso clínico / Cystic degeneration of the popliteal artery: Report of one case

Cystic degeneration of the popliteal artery is an uncommon cause of intermittent claudication. We report a 52 years old male consulting for intermittent claudication referred to the calf. The angiography showed a 93% stenosis in segment of 45 mm length of the left popliteal artery with a smooth surface, suggesting an extrinsic compression. A CT angiography of the lower limb suggested the presence of a cystic degeneration. The patient was operated and the middle third of the popliteal artery was excised. The pathological study of the surgical piece was informed as artery media cystic degeneration.

Uterine carcinosarcoma/malignant mixed Mullerian tumor incidence is increased in women with breast cancer, but independent of hormone therapy / 부인종양

No abstract available.

The sero-prevalence of Toxoplasma gondii in British marine mammals

Serum samples from 101 stranded or bycatch cetaceans from British waters were screened for Toxoplasma gondii-specific antibodies using the Sabin Feldman Dye Test. Relatively high seropositivity was recorded in short-beaked Delphinus delphis and this study presents the first documented case of Toxoplasma in a humpback whale Megaptera novaeangliae.

Surgical excision of periocular basal cell carcinomas.

The purpose of this study was to determine the histological clearance and clinical recurrence rates following excision of primary periocular biopsy-proven basal cell carcinomas (BCCs) in a teaching hospital in United Kingdom and compare it with other published reports. Records of consecutive patients with a biopsy proven diagnosis of primary periocular BCCs treated surgically at our hospital between 1995 and March 2003 were reviewed. Twenty seven cases (25 patients) were identified. Intra-operative frozen sections (IFS) were performed in 17 (63%) of the cases with clear margins on IFS in 16/17 (94%) of these cases. Histology revealed complete excision in 25/27 (92.5%) of cases. The results of excision of periocular BCCs in our setting particularly with IFS are comparable with other published reports. A reaudit is recommended in 5 years to allow a larger patient population with greater follow up, which would enable us to give more definitive judgment on this treatment modality.

Specific language impairment: effect on later language development: a literature review.

BACKGROUND: Children with specific language impairment (SLI) are at considerable risk for later language development. However there has not been a good literature review to provide understanding and to get information relative to parental counseling and decision making for further management. OBJECTIVE: To summarize the literature review on SLI and effect on later language development. MATERIAL AND METHOD: Longitudinal studies were systematically explored to seek evidence- based information to confirm the lasting effect of SLI in later language development. RESULTS: Natural history data indicated that approximately 50% of children with specific expressive language delay spontaneously remitted or outgrew it at age 5-8. However, long-term follow-up studies showed their language problems emerged later at age 15. The rest of the children's (50%), language impairment persisted and had a high risk for SLI later. CONCLUSION: The results suggest that active intervention should be performed as soon as possible for children with persisting SLI.

Streptococcus milleri group bacteraemia in North Yorkshire, England (1989-2000).

BACKGROUND & OBJECTIVES: Though carriage and local infection with organisms of the Streptococcus milleri group (SMG) are regular in clinical practice, bacteraemia is infrequent in man. The objective of the present study was to give an account of our experience with the SMG bacteraemia over a period of 12 yr in North Yorkshire. METHODS: The laboratory and clinical records of all clinically significant cases of SMG bacteraemia in our district general hospital catchment (combined population 260,000) were reviewed for the 12 yr period from 1989 to 2000. Viable isolates were recovered, species identified, and minimum inhibitory concentration (MIC) determined. RESULTS: Twenty nine episodes of infection gave an annual incidence of 0.93 cases per 100,000 population. Infections included abscess, pneumonia, septic arthritis, genital and urinary tract infections, endocarditis and diffuse septicaemia. Patient ages ranged from 18 to 90 yr but most patients were elderly, 82 per cent had evident predisposing conditions and mortality rate was 10 per cent. Species determination of the 22 isolates showed S. anginosus (64%), S. constellatus (27%) and S. intermedius (9%). Nearly all isolates were non-haemolytic and Lancefield grouping showed carriage of the F antigen (in 41%), C (14%) and no detected group (45%). Most of the isolates were susceptible to the antimicrobials tested. INTERPRETATION & CONCLUSION: Bacteraemia with SMG organisms was infrequent, often opportunistic and featured a low overall mortality rate. Intra-abdominal sepsis was the local feature in 16 (55%) of the patients and 9 (31%) of the total patient group showed abscess or empyema. There was a low rate of antibiotic resistance in these organisms from bloodstream infection.

Changing incidence of detected streptococcal bacteraemia in North Yorkshire, England.

BACKGROUND & OBJECTIVES: Streptococcal bacteraemia remains a major and challenging clinical problem throughout the world. The epidemiology of these infections appears to be changing. In the present study we analysed the data collected over a period of 20 yr (1978-1999) to throw light on this. METHODS: Laboratory records of all patients yielding clinically significant, non-pneumococcal, nonenterococcal streptococcal bacteraemia were reviewed for the decades 1978-1988 and 1990-1999 in the two districts (combined population 260,000). RESULTS: From a total of 3134 patients with detected bacteraemia 338 (10.8%) yielded streptococci. The organisms comprised: in the beta-haemolytic group (n=169), GAS (32%), GBS (34%), GCS (5%), GGS (28%), GRS (1%); in the non-haemolytic/Streptococcus milleri group (n=160): S. milleri (21%), S. bovis (10%), S. sanguis (30%), S.mitis (10%), S. oralis (8%) and other 'viridans' streptococci (20%); nine isolates were of anaerobic streptococci. There was a steady increase in the number of blood cultures submitted for investigation during the period and streptococcal isolations of all species rose in proportion (approximately x 2.5) in the second decade compared with the first. Complementary data on the occurrence of necrotising fasciitis and toxic shock syndrome in these districts suggested a real increase in the occurrence of serious forms of GAS infection. INTERPRETATION & CONCLUSION: An increase in the level of detected streptococcal bacteraemia was seen in this part of England over 20 yr, involving a wide variety of different streptococcal species. This represented both improved ascertainment of infection and an increase in the burden of disease in the population.

Flúor: bebida aditivada / Fluoride: additived drinks

Países como Chile, China, Bulgária e Inglaterra aplicam flúor no leite para combater a cárie infantil. Alternativa é recomendada pela Organização Mundial da Saúde (OMS) onde não é possível implantar a fluoretação do sal ou até mesmo da água. No Brasil, a água fluorada vem diminuindo drasticamente a incidência de cáries na população

Doenças cardiovasculares: comentários sobre a mortalidade precoce no Brasil / Cardiovascular Diseases. Comments on Early Mortality in Brazil

Objetivo - Comparar coeficientes de mortalidade por infarto agudo do miocárdio (IAM) e doenças cerebrovasculares, específicos por idade em capitais situadas em regiöes metropolitanas do Brasil, às taxas de outros países. Métodos - Os dados de mortalidade das capitais brasileiras foram obtidos a partir do Sistema de Informaçäo de Mortalidade, do Ministério da Saúde. Os óbitos e taxas de mortalidade relativos aos outros países foram obtidos a partir de publicaçäo especializada da Organizaçäo Mundial de Saúde. Resultados - Nas capitais estudadas, cerca de 50 por cento dos ósbitos masculinos por doença isquêmica do coraçäo ocorreram no grupo etário menor de 65 anos de idade, enquanto em outros países, esta proporçäo situou-se em torno dos 25 por cento. O risco de morrer por IAM nos homens, entre 35 e 44 anos, foi 3 vezes mior do que o norte-americano. Os coeficientes de mortalidade por doenças cerebrovasculares também apresentaram maior magnitude em nosso meio, comparando-se aos outros países estudados. Conclusäo - Ao contrário do que se imagina, as enfermidades cardiovasculares näo constituem, no Brasil, causa de óbito importante apenas nos grupos mais idosos. Estes resultados sugerem a necessidade de investigaçäo específica em nosso meio, bem como a urgência da implantaçäo de programas de controle

Aspectos psiquiátricos e neurológicos da síndrome de Capgras e de outros distúrbios de identificaçäo correlatos / Psychiatric and neurologic aspects of Capgras syndrome and other disorders of correlates identification

Foram avaliados 260 relatos de caso sobre distúrbios de identificaçäo. Destes, 174 pacientes apresentavam síndrome de Capgras, 18 síndrome de Frégoli, 11 intermetamorfose, 17 síndrome do duplo subjetivo, 17 paramnésia reduplicativa e o restante combinaçöes de dois ou mais destes. O sexo e a idade média dos pacientes näo mostraram diferenças significativa. Sintomas psicóticos foram significativamente mais prevalentes (p < 0,005) em pacientes com sídrome do duplo subjetivo. Esquizofrenia, distúrbio de humor e síndromes mentais orgânicas foram menos freqüentemente descritas em pacientes com paramnésia reduplicativa. Estes, por sua vez, apresentavam maior prevalência de traumatismo craniano (p < 0,05) e lesöes focais de hemisférico cerebral direito (p < 0,005). A diferença entre o quociente de inteligência verbal e de desempenho encontrada sugere que os pacientes com paramnésia reduplicativa (p < 0,01) apresentam disfunçäo de hemisférico direito mais severa que os demais grupos. A identificaçäo errônea de outras pessoas (síndrome de Capgras, Frégoli e intermetamorfose) ou de si mesmo (síndrome do duplo subjetivo) pode ser expressäo de um quadro psicótico de natureza psiquiátrica ou orgânica, enquanto paramnésia reduplicativa está mais comumente associada a doenças neurológicas, particularmente quando estas afetam o hemisfério direito. A prevalência dos distúrbios de identificaçäo é possivelmente subestimada

Perinatal and postneonatal mortality in England and Wales among immigrants from the Indian subcontinent.

Perinatal and postneonatal mortality among immigrants to England and Wales from India, Pakistan and Bangladesh (Asians) for the years 1982-85 showed significant differences not only between the immigrant and indigenous populations, but also among the different groups from the Indian subcontinent. Compared with the perinatal mortality rate of 10.1 per 1000 total births in UK born mothers, rates in infants of mothers born in India, Bangladesh, and Pakistan were 12.5, 14.3 and 18.8 respectively. In contrast, postneonatal mortality in infants of Indian and Bangladeshi origin (3.9 and 2.8 per 1000 live births respectively) was lower than in the indigenous population (4.1), with Pakistani infants experiencing the highest rate (6.4). Excess perinatal mortality in infants of Asian origin was apparent at most maternal ages and parities. Pakistani infants had the highest rates of perinatal and postneonatal mortality in all age, parity and birth weight groups. The Asian groups showed higher mortality from congenital anomalies in both the perinatal and the postneonatal period, the rates in Pakistani infants being almost double those in Indian and Bangladeshi infants. A significant finding was the lower rates of sudden infant death in all the groups of Asian origin.